منابع مشابه
Halothane and liver damage.
The Medical Assessor to the Committee on Safety ofMedicines recently issued' a letter entitled "Jaundice following repeated exposure to halothane," in which he noted that 130 reports of jaundice following anaesthesia had been received by the committee between 1964 and 1972, every case being associated with the use of halothane. Ninety-four of these patients had been exposed to halothane more th...
متن کاملHalothane and liver damage.
Halothane was first synthesized by Suckling in 1952 and introduced into clinical practice a few years later.',2 Its many advantages, such as quick action, easy administration, non-explosiveness, high potency and low cost, led to its widespread use within a short time. Although initial animal work did not indicate any hepatotoxic effect,3`5 the first cases of unexplained hepatitis after exposure...
متن کاملHalothane anaesthesia and liver damage.
A recent experience of the senior author when addressing a meeting of anaesthetists prompted this review, since it was apparent that there was still considerable disagreement between hepatologists and anaesthetists over the association between liver cell damage and halothane anaesthesia and the measures by which the risk could be minimised. Although during the 1960s and 1970s the evidence was h...
متن کاملHepatocellular damage due to halothane anaesthesia.
To determine the hepatotoxic effect of halothane anaesthesia, liver function tests were done a day prior to surgery in 41 cases undergoing various elective operations. The tests were repeated on 7th post operative day to see the derangement. Statistically significant rise in serum bilirubin, ALT and alkaline phosphatase was found post-operatively. As certain groups of patients are more prone to...
متن کاملA comparison between the effect of halothane and propofol on liver enzymes after general anesthesia
Background: Halothane is the routine used inhalation anesthetic drug in the world but at present, there is an increasing interest for using intravenous anesthetics like propofol. The purpose of this study was to compare these anesthetic effects on hepatic enzymes.Methods: From 2006 to 2007, this study was performed on fifty eight patients classified in class I of American Society of Anesthetics...
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ژورنال
عنوان ژورنال: BMJ
سال: 1974
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5934.807-b